Nepal Eye Program, Tilganga Institute of Ophthalmology is a tertiary referral center for eye diseases in Nepal. In 2016 AD a total of 235,907 patients were treated from the base hospital of TIO. Out of these a total of 20,654 surgeries were performed. The male female ratio was almost similar at TIO. Similarly in the same year a total of 227,903 cases were treated from community eye care program of TIO. There were 29 Outreach Micro Surgical Eye camps were organized in 2016 of which 5 were out of Nepal including India, Bhutan, and Myanmar.

The TIO research department was established in 2002. The main purpose of the research department is to facilitate the practice of evidence based research in policy making and delivery of eye care to eliminate avoidable blindness. Within the short period of time the research department has conducted more than 100 research projects and more than 160 research papers have been published in national and international indexing journal. These researches are mainly from clinical and public health areas. The ground breaking research conducted by the team of Dr Sanduk Ruit on manual small incision cataract surgery was an innovation that was able to eliminate that established low cost, high volume and high quality cataract surgery. This innovation on manual cataract surgery techniques has revolutionized the approach to eliminating avoidable blindness globally.